The name Oxycontin was first made in Germany in 1916 from thebaine.It is available as a generic medication.In 2017, it was the 52nd most commonly prescribed medication in the United States, with more than 15 million prescriptions.A number of abuse-deterrent formulations are available, such as in combination with naloxone. sold under the brand name OxyContin among others, is an opioid medication used for treatment of moderate to severe pain, and a common drug of abuse.It is usually taken by mouth, and is available in immediate-release and controlled-release formulations.Onset of pain relief typically begins within 15 minutes and lasts for up to six hours with the immediate-release formulation.In the United Kingdom, it is available by injection.Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, and aspirin.
What Is OxyContin and how is it used?
It is a prescription medicine used to treat moderate to severe pain. Oxycontin may be used alone or with other medications. Adults over 18 years:OxyContin tablets should be taken at 12-hourly intervals. The dosage is dependent on the severity of the pain, and the patient’s previous history of analgesic requirements.Prior to starting treatment with opioids, a discussion should be held with patients to put in place a strategy for ending treatment with oxycodone in order to minimise the risk of addiction and drug withdrawal syndrome. Increasing severity of pain will require an increased dosage of OxyContin tablets, using the 5 mg, 10 mg, 20 mg, 40 mg or 80 mg tablet strengths, either alone or in combination, to achieve pain relief. The correct dosage for any individual patient is that which controls the pain and is well tolerated for a full 12 hours. Patients should be titrated to pain relief unless unmanageable adverse drug reactions prevent this. If higher doses are necessary, increases should be made in 25% – 50% increments. The need for escape medication more than twice a day indicates that the dosage of OxyContin tablets should be increased.The usual starting dose for opioid naïve patients or patients presenting with severe pain uncontrolled by weaker opioids is 10 mg, 12-hourly. Some patients may benefit from a starting dose of 5 mg to minimise the incidence of side effects. The dose should then be carefully titrated, as frequently as once a day if necessary, to achieve pain relief. For the majority of patients, the maximum dose is 200 mg 12-hourly. However, a few patients may require higher doses. Doses in excess of 1000 mg daily have been recorded.
common side effects